Related Experiment Video
Updated: Jun 23, 2026

CD Spectroscopy to Study DNA-Protein Interactions
Published on: February 10, 2022
OMWSA: detection of DNA repeats using moving window spectral analysis
Liping Du1, Hongxia Zhou, Hong Yan
1Department of Electronic Engineering, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong.
Unlabelled:
Repetitive DNA sequences play paramount biological roles, such as gene variation and regulatory functions on gene expressions. Until now, detection of various kinds of DNA repeats accurately is still an open problem. In this article, we propose a new method and a visualization tool for detecting DNA repeats in a 2D plane of location and frequency by using optimized moving window spectral analysis. The spectrogram can display the general distribution of repetitive sequences while showing the repeat period, length and location without any prior knowledge. Experimental results demonstrate that our method is accurate and robust even under the condition of excessive mutating and interleaving.
Availability:
Available on http://www.hy8.com/~tec/sw01/omwsa01.zip.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
Related Concept Videos
DNA Microarrays
IR Frequency Region: Fingerprint Region
The...

