Early detection of disturbances of epithelial keratinization

Unsatisfactory results treatment of the hypopharyngeal and upper respiratory tract carcinoma lead us to investigations on the efficient diagnostic methods of keratinization disturbances. We used a method worked out earlier in our Clinic and based on cytologic examinations of Papanicolaou. In present series we performed cytologic examinations in patients from high-risk groups of the upper respiratory tract and hypopharyngeal cancer. In any doubt cytology was accompanied by histological examination. Our material judges the statement that cytological examination may be used as a screening method of examination in prophylaxis of hypopharyngeal cancer.