Related Experiment Video
Updated: Jul 17, 2026
Partial Lobular Hepatectomy: A Surgical Model for Morphologic Liver Regeneration
Published on: May 31, 2018
Amelioration of aluminium-induced liver damage by vitamin E
Recep Kutlubay1, Emin O Oguz, Gulcin Abban
1Department of Histology and Embryology, Kinikli, Denizli, Turkey.
Objective:
To investigate the effects of aluminium sulphate on the microscopic morphology of the liver and on vitamin E amelioration of aluminium-induced liver damage.
Methods:
Rats were injected intraperitoneally with aluminium sulphate alone or aluminium sulphate together with vitamin E, with saline injected rats used as the control group. The study took place in Pamukkale University Faculty of Medicine in 2005.
Results:
The rats exposed to aluminium showed morphological changes in addition to previously reported biochemical changes in the liver. The anti-oxidant vitamin E significantly diminished the liver damage seen due to aluminium.
Conclusion:
There is an apparent protective effect of vitamin E on parenteral aluminium exposure.
