Triterpenoid Saponins from Caltha palustris

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Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
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Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale

Published on: August 16, 2018

P Bhandari1, A I Gray, R P Rastogi

  • 1Department of Pharmacognosy, School of Pharmacy, Trinity College Dublin, 18 Shrewsbury Road, Dublin 4, Ireland.

Planta Medica
|February 1, 1987
PubMed

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Esters to Carboxylic Acids: Saponification01:25

Esters to Carboxylic Acids: Saponification

Esters can be hydrolyzed to carboxylic acids under acidic or basic conditions. Base-promoted hydrolysis of esters is a nucleophilic acyl substitution reaction in which esters react with an aqueous base, followed by an acid to give carboxylic acids. This reaction is also known as saponification because it forms the basis for making soaps from fats.
The reaction requires a base in stoichiometric amounts, which participates in the reaction and is not regenerated later. So, the base acts as a...