Investigation of the Alkaloid Pattern of Datura innoxia Plants by Capillary Gas-Liquid-Chromatography-Mass Spectrometry
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Updated: Jul 17, 2026

Applications of Liquid-Chromatography Tandem Mass Spectrometry in Natural Products Research: Tropane Alkaloids as a Case Study
Published on: March 8, 2024
L Witte1, K Müller, H A Arfmann
1Gesellschaft für Biotechnologische Forschung mbH, Mascheroder Weg 1, D-3300 Braunschweig, Federal Republic of Germany.
Abstract:
The alkaloid composition of DATURA INNOXIA plants was analysed by quartz capillary GLC and GLC-MS. Significant differences were found in the alkaloid pattern of the respective plant organs even between different aerial parts. More than 30 alkaloids could be identified. Besides previously known substances, a further 18 tropine ester alkaloids as well as hygrine and tyramine were identified. Seventeen of these alkaloids have not been formerly found in the genus DATURA. Additionally, two hitherto unknown hygrine derivatives, presumably isomeric N-methylpyrrolidinyl-hygrines, were characterized.
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