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Updated: Jul 17, 2026

Applications of Liquid-Chromatography Tandem Mass Spectrometry in Natural Products Research: Tropane Alkaloids as a Case Study
Published on: March 8, 2024
Abstract:
A new strychnos-type alkaloid, bharhingine ( 1), has been isolated from the leaves of RHAZYA STRICTA. Its structure has been assigned on the basis of spectral studies including 2D-NMR measurements. The structure and stereochemistry of another Aspidosperma-type alkaloid, strictanol ( 2) has been investigated by extensive NMR studies including hetero-COSY experiments and NOE difference measurements. Isolation of another strychnos-type alkaloid, vincanicine ( 3), not previously reported from this plant, is also described.
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