Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Biosynthesis of Polysaccharides

Biosynthesis of Polysaccharides

Polysaccharides such as glycogen and starch are synthesized from nucleoside diphosphate sugars, primarily uridine diphosphate glucose (UDPG) and adenosine diphosphate glucose (ADPG). These activated glucose donors act as key intermediates in carbohydrate metabolism and biosynthesis. UDPG primarily involves glycogen synthesis in animals and many bacteria, while ADPG plays a fundamental role in starch synthesis in plants and certain bacteria.UDPG is formed when glucose-1-phosphate reacts with...

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors

α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
Acarbose and miglitol are typically...

Cellulose and Pectic Polysaccharides

Cellulose and Pectic Polysaccharides

Every plant cell has a cell wall that protects the cell, provides structural support, and gives the cell shape. Cellulose, the main structural component of the plant cell wall, makes up over 30% of plant matter. It is the most abundant organic compound on earth. Cellulose is an unbranched polysaccharide composed of linear chains of glucose molecules linked by β (1→4) glycosidic bonds.
As a cell matures, its cell wall specializes according to its type. For example, the parenchyma cells of...

Proteoglycans

Proteoglycans

Glycans, a class of complex heterogeneous molecules, can be covalently attached to proteins to form glycosylated proteins that regulate various physiological and pathological processes. Glycosylated proteins or glycoproteins comprise N-linked and O-linked oligosaccharides. O-glycosylation is the most common type of protein glycosylation. Here, glycans attach to the oxygen atom of the hydroxyl groups of Serine or Threonine residues. O-linked glycosylation occurs later in protein processing,...

Preparation of Diols and Pinacol Rearrangement

Preparation of Diols and Pinacol Rearrangement

Compounds bearing two hydroxyl groups are known as diols. When the hydroxyl groups are located on adjacent carbon atoms, the diols are called vicinal diols or glycols. Under acidic conditions, vicinal diols undergo a specific reaction called pinacol rearrangement.
The reaction begins with transferring a proton from the acid catalyst to one of the hydroxyl groups, producing an oxonium ion.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Photoinduced properties of anodized Ti alloys for biomaterial applications.

Scientific reports·2023

Same author

Favorable clinical response and drug retention of anti-IL-6 receptor inhibitor in rheumatoid arthritis with high CRP levels: the ANSWER cohort study.

Scandinavian journal of rheumatology·2021

Same author

Lack of association between a disease-susceptible single-nucleotide polymorphism, rs2230926 of <i>TNFAIP3</i>, and tumour necrosis factor inhibitor therapeutic failure in Japanese patients with rheumatoid arthritis.

Scandinavian journal of rheumatology·2020

Same author

Myositis with sarcoplasmic inclusions in Nakajo-Nishimura syndrome: a genetic inflammatory myopathy.

Neuropathology and applied neurobiology·2020

Same author

Bioactive TiNbSn alloy prepared by anodization in sulfuric acid electrolytes.

Materials science & engineering. C, Materials for biological applications·2019

Same author

Utility of osteopontin in cerebrospinal fluid as a diagnostic marker for neuropsychiatric systemic lupus erythematosus.

Lupus·2019

Search research articles

Related Experiment Video

Updated: Jul 17, 2026

Screening and Isolation of C-Glycoside-Cleaving Intestinal Bacteria

Screening and Isolation of C-Glycoside-Cleaving Intestinal Bacteria

Published on: February 28, 2025

Polygoacetophenoside, A New Acetophenone Glucoside from Polygonum multiflorum1.

M Yoshizaki¹, H Fujino, A Arise

¹Department of Herbal Garden, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930-01, Japan.

|June 1, 1987

Summary

A new compound, polygoacetophenoside, was identified in Polygonum multiflorum. This acetophenone glucoside was characterized using chemical and spectral analyses.

More Related Videos

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC

Published on: February 2, 2024

Comparative Study on the Polysaccharide Contents and Antioxidant Activities of Hippophae rhamnoides subsp. sinensis and Hippophae gyantsensis

Comparative Study on the Polysaccharide Contents and Antioxidant Activities of Hippophae rhamnoides subsp. sinensis and Hippophae gyantsensis

Published on: August 15, 2025

Related Experiment Videos

Last Updated: Jul 17, 2026

Screening and Isolation of C-Glycoside-Cleaving Intestinal Bacteria

Screening and Isolation of C-Glycoside-Cleaving Intestinal Bacteria

Published on: February 28, 2025

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC

Published on: February 2, 2024

Comparative Study on the Polysaccharide Contents and Antioxidant Activities of Hippophae rhamnoides subsp. sinensis and Hippophae gyantsensis

Comparative Study on the Polysaccharide Contents and Antioxidant Activities of Hippophae rhamnoides subsp. sinensis and Hippophae gyantsensis

Published on: August 15, 2025

Area of Science:

Phytochemistry
Natural Product Chemistry
Organic Chemistry

Background:

Polygonum multiflorum is a traditional medicinal plant with a rich history of use.
The plant is known to contain various bioactive compounds, including flavonoids and phenolic acids.
Further investigation into its chemical constituents can reveal novel therapeutic agents.

Purpose of the Study:

To isolate and characterize new compounds from Polygonum multiflorum.
To elucidate the chemical structure of an unknown acetophenone glucoside.
To contribute to the understanding of the phytochemical diversity of Polygonum species.

Main Methods:

Phytochemical investigation of Polygonum multiflorum extract.
Isolation of compounds using chromatographic techniques (e.g., column chromatography).
Structure elucidation through comprehensive spectroscopic analyses (e.g., NMR, MS) and chemical methods.

Main Results:

Isolation of three compounds: quercetin 3-O-galactoside (1), quercetin 3-O-arabinoside (2), and a new acetophenone glucoside, polygoacetophenoside (3).
The structure of the new compound was determined to be 2,3,4,6-tetrahydroxyacetophenone 3-O-beta-D-glucoside.
Compounds 1 and 2 were identified as known quercetin glycosides.

Conclusions:

Polygoacetophenoside is a novel acetophenone glucoside isolated from Polygonum multiflorum.
The structural elucidation provides valuable data for the chemical characterization of this plant.
This discovery adds to the known phytochemical profile of Polygonum species and may warrant further pharmacological evaluation.