[Placental changes in toxicoses in the second half of pregnancy]

An investigation of 88 placentas in toxicosis of the second half of pregnancy has detected symptoms of the immune alteration detailed by means of an electron microscopic analysis and immunomorphological investigations with the help of luminescent sera against immunoglobulins A, M. G and C3 fraction of complement. The alterations found are indicative of the participation of immune mechanisms in the formation of placental insufficiency and their important role in pathogenesis of gestational toxicosis.