Related Experiment Video
Updated: Jul 17, 2026

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling
Published on: November 3, 2015
A two-layer model of the static behaviour of blood vessel walls
1Department of Engineering Science, University of Oxford, UK.
Abstract:
A model is presented that simulates the steady state two-layer nature of blood vessel walls. The model comprises an intimal-medial layer and an adventitial layer, both of which are modeled using previously validated separate models. By including both models, different types of blood vessel can be modeled within a common framework. The necessary relationships that link the two models are presented and simulations of the complete model shown. These illustrate how different types of vessel exhibit different non-linear behaviour. The models include both mechanical and biochemical aspects of the vessel wall behaviour, which will enable the model to be used to simulate more advanced behaviour such as local autoregulatory processes.
More Related Videos
06:18Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery
Published on: December 6, 2024
13:07Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Related Concept Videos
Structure of Blood Vessels
Overview of the Vascular System
Boundary Layer Characteristics
Navier–Stokes Equations
Autoregulation of Blood Flow
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
Applications of Integration to Find Blood Flow