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Updated: Jul 17, 2026

Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression
Published on: December 10, 2014
A novel statistical model for simulation of arterial and intracranial pressure
1Biomedical Signal Process. Laboratory, Electr. & Comput. Eng., Portland State Univ., USA.
Abstract:
We describe a novel statistical model of pressure signals that incorporates the effects of respiration on arterial (ABP) and intracranial pressure (ICP). This model can be used to synthesize pulsatile ABP and ICP signals with similar time, frequency, and variability characteristics of real pressure signals. These synthetic signals can be used during the development, simulation, or quantitative assessment of biomedical algorithms in a variety of applications.
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