Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multi-class cancer classification by semi-supervised ellipsoid ARTMAP with gene expression data.

Rui Xu1, Georgios C Anagnostopoulos, Donald C Wunsch

  • 1Dept. of Electr. & Comput. Eng., Missouri Univ., Rolla, MO 65409-0249, USA.

Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
|February 3, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Current state of the art of new prostate MRI technologies and potential future developments.

BJR open·2026
Same author

Prostate Cancer: Current Status of Novel Molecular Imaging and Future Prospects.

European urology focus·2025
Same author

DeepART: Deep gradient-free local learning with adaptive resonance.

Neural networks : the official journal of the International Neural Network Society·2025
Same author

Adaptive Nussbaum Design for Nonholonomic Systems With Asymptotic Stabilization Against False Data Injection.

IEEE transactions on cybernetics·2025
Same author

A Generalized Time Rescaling Theorem for Temporal Point Processes.

Neural computation·2025
Same author

A multi-firearm, multi-orientation audio dataset of gunshots.

Data in brief·2023
Same journal

Highly Articulated Robotic Probe for Minimally Invasive Surgery.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference·2010
Same journal

Combined peripheral and cortical neural stimulation in motor neurorehabilitation.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference·2008
Same journal

Embedded assessment algorithms within home-based cognitive computer game exercises for elders.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference·2008
Same journal

Digital signal processing of the wideband external pulse recorded during cuff deflation: a new way to measure blood pressure.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference·2008
Same journal

Immune cells detection of the in vivo rejecting heart in USPIO-enhanced magnetic resonance imaging.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference·2008
Same journal

wHospital: a web-based application with digital signature for drugs dispensing management.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference·2007
See all related articles

This study shows that semi-supervised ellipsoid ARTMAP (ssEAM), a novel neural network, can effectively classify multi-class cancer using gene expression profiles. ssEAM offers a promising approach for accurate cancer diagnosis and treatment planning.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Machine Learning in Oncology

Background:

  • Accurate tumor origin identification is vital for cancer diagnosis and treatment.
  • Gene expression profiling using DNA microarrays is a key method for cancer classification.
  • Distinguishing between multiple cancer types presents a significant challenge.

Purpose of the Study:

  • To evaluate the efficacy of semi-supervised ellipsoid ARTMAP (ssEAM) for multi-class cancer discrimination.
  • To demonstrate ssEAM's capability in analyzing gene expression data for cancer classification.
  • To introduce ssEAM as a novel neural network for complex classification tasks.

Main Methods:

  • Utilized semi-supervised ellipsoid ARTMAP (ssEAM), a neural network based on adaptive resonance theory.

Related Experiment Videos

  • Applied ssEAM to analyze two publicly available cancer datasets.
  • Leveraged gene expression profiles as input for the classification models.

    • Main Results:

    • ssEAM successfully discriminated between multiple cancer types.
    • The neural network demonstrated fast, stable, and finite learning capabilities.
    • ssEAM created hyper-ellipsoidal clusters, enabling complex nonlinear decision boundaries.

    Conclusions:

    • ssEAM is a capable tool for multi-class cancer discrimination using gene expression data.
    • The findings support ssEAM's potential in advancing cancer classification and diagnosis.
    • This study highlights the utility of adaptive resonance theory-based networks in bioinformatics.