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Updated: Jul 17, 2026

Corneal Tissue Engineering: An In Vitro Model of the Stromal-nerve Interactions of the Human Cornea
Published on: January 24, 2018
3D average human corneal models
J F Laliberte1, I Brunette, J Meunier
1Ophtalmology Res. Unit, Maisonneuve-Rosemont Hosp., Montreal, Que., Canada.
Abstract:
In this paper we propose a method of building an average model or atlas of the cornea based on topographic data. Specific models can be constructed for the left or right eye, gender, age, or ametropia, to assess differences and similarities. An application of this atlas construction methodology to the study of corneal shape evolution with age is presented. Results show significant differences between age groups. This numerical atlas could also be helpful in the design of algorithms targeting the detection of corneal shape abnormalities, such as keratoconus or previous laser surgery.
