Related Experiment Video
Updated: Jul 17, 2026

Intradermal Microdialysis: An Approach to Investigating Novel Mechanisms of Microvascular Dysfunction in Humans
Published on: July 21, 2023
Racial and ethnic differences in cardiovascular disease risk factors: a systematic review
Anita K Kurian1, Kathryn M Cardarelli
1School of Public Health, University of North Texas Health Science Center, Plano; Tarrant County Public Health, Fort Worth, Texas, USA. akkurian@tarrantcounty.com
Insights
Racial and ethnic minorities face higher cardiovascular disease (CVD) risks like hypertension and diabetes. Understanding these disparities is key to developing targeted prevention programs for diverse populations.
Area of Science:
- Public Health
- Cardiovascular Medicine
- Health Disparities Research
Background:
- Cardiovascular diseases (CVD) are a leading cause of death in the U.S.
- Racial and ethnic minority populations experience disproportionately higher CVD rates.
- Understanding modifiable CVD risk factors is crucial for these populations.
Purpose of the Study:
- To examine factors associated with racial/ethnic disparities in CVD risk factors.
- To assess differences in hypertension, diabetes, obesity, hypercholesterolemia, physical activity, and smoking by race/ethnicity.
- To update and expand upon existing reviews of CVD risk factor disparities.
Main Methods:
- Systematic review of English-language, population-based CVD studies.
- Inclusion criteria: studies published from 1995 to present with adult populations and ethnic comparisons.
- Analysis focused on prevalence of key CVD risk factors across different racial/ethnic groups.
Main Results:
- Hypertension prevalence was significantly higher in Black populations compared to White populations.
- Minority status was significantly associated with higher diabetes prevalence.
- Prevalence of obesity and hypercholesterolemia did not consistently differ across minority groups.
- Smoking rates were lower in Mexican Americans but higher in American Indian/Alaskan Natives (AIANs) compared to Whites.
- Mexican Americans, AIANs, and Blacks showed higher rates of no leisure-time physical activity.
Conclusions:
- Significant racial and ethnic disparities exist in cardiovascular disease risk factors.
- Awareness of these disparities is vital for developing culturally sensitive interventions.
- Targeted prevention programs and services are needed to address specific risk burdens in diverse populations.
Objective:
This systematic review was undertaken to expand our understanding of the factors associated with racial/ethnic disparities in cardiovascular disease (CVD) risk factors (hypertension, diabetes, obesity, hypercholesterolemia, no leisure-time physical activity, and smoking), to assess the potential differences in the CVD risk factors by race/ethnicity, and to update and expand on existing reviews.
Methods:
English-language, population-based CVD studies published between 1995 to present, which included one or more ethnic comparison in an adult population were reviewed.
Results:
Sixteen studies were included in this review. Most of the studies found hypertension to be significantly higher in Blacks than Whites. Minority status was also significantly associated with diabetes. No one racial/ethnic minority population was consistently found to have a higher or lower prevalence of obesity or hypercholesterolemia. Mexican Americans had a significantly lower prevalence of smoking than Whites and Blacks; American Indian/Alaskan Natives (AIANs) had significantly higher prevalence of smoking compared to Whites. Mexican Americans had the highest prevalence of no leisure-time physical activity, followed by AIANs and Blacks.
Conclusion:
Cardiovascular diseases are the leading cause of death in the United States, and disproportionate rates are seen in racial and ethnic minority populations. Systematically assessing and quantifying modifiable CVD risk factors is therefore crucial in these populations. Better understanding and awareness of the disparities of CVD risk factors by race and ethnicity may help clinicians and public health professionals develop culturally sensitive interventions, prevention programs, and services specifically targeted toward risk burdens in each of these populations.
Related Concept Videos
Coronary Artery Disease I: Introduction
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Coronary Artery Disease IV: Preventive Measures
Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Atherosclerosis III: Management