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Updated: Jul 17, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
Heart rate variability in patients with allergic rhinitis
Mehmet Yokusoglu1, Sami Ozturkt, Mehmet Uzun
1Cardiology Department, Gulhane Military Medical Academy School of Medicine, Ankara, Turkey.
Patients with allergic rhinitis exhibit increased heart rate variability (HRV) indices, suggesting heightened parasympathetic activity. This indicates vagal activation extends beyond the respiratory system to influence cardiovascular function in allergic rhinitis.
Area of Science:
- Immunology
- Cardiology
- Autonomic Neuroscience
Background:
- Autonomic imbalance is implicated in hypersensitivity reactions.
- Allergic rhinitis is a common condition affecting the respiratory system.
Purpose of the Study:
- To investigate autonomic system function in allergic rhinitis patients.
- To analyze heart rate variability (HRV) using time-domain methods.
Main Methods:
- Enrolled 24 allergic rhinitis patients and 22 healthy controls.
- Conducted 24-hour ambulatory electrocardiographic recordings.
- Analyzed time-domain HRV indices.
Main Results:
- Patients with allergic rhinitis showed significantly greater root mean square successive difference, number of RR intervals >50ms, and percentage difference between adjacent normal RR intervals >50ms.
- Indices predicting parasympathetic predominance were elevated in the allergic rhinitis group.
- SD of normal RR intervals, SD of successive differences, and HRV triangular index did not differ significantly.
Conclusions:
- Increased HRV indices in allergic rhinitis suggest parasympathetic predominance.
- Vagal activation in allergic rhinitis impacts both nasal and cardiovascular systems.
- Autonomic nervous system plays a significant role in allergic rhinitis pathogenesis.
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