Hemorrhagic stroke in children

Lori C Jordan1, Argye E Hillis

  • 1Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA. ljordan2@jhmi.edu

Pediatric Neurology
|February 6, 2007
PubMed

Insights

Childhood hemorrhagic stroke is common, yet lacks treatment guidelines. This review highlights key differences from adult cases and discusses evaluation, treatment, and outcomes for pediatric patients.

Area of Science:

  • Pediatric Neurology
  • Neurocritical Care
  • Pediatric Stroke

Background:

  • Hemorrhagic stroke comprises about 50% of childhood stroke cases.
  • Unlike arterial ischemic stroke, there are no established consensus guidelines for pediatric hemorrhagic stroke evaluation and treatment.
  • Significant differences exist between pediatric and adult hemorrhagic stroke, making adult treatment protocols potentially inapplicable to children.

Purpose of the Study:

  • To review the current literature on the evaluation, treatment, etiology, and neurologic outcomes of hemorrhagic stroke in children.
  • To highlight critical distinctions between pediatric and adult hemorrhagic stroke.
  • To identify areas for future research and potential therapeutic strategies.

Main Methods:

  • Comprehensive literature review of pediatric hemorrhagic stroke.
  • Analysis of studies focusing on evaluation, treatment, etiology, and neurologic outcomes.
  • Comparison of pediatric and adult hemorrhagic stroke characteristics.

Main Results:

  • Hemorrhagic stroke is a major cause of stroke in children.
  • Pediatric hemorrhagic stroke management requires specific considerations distinct from adult protocols.
  • Etiologies and outcomes in children vary and necessitate tailored approaches.

Conclusions:

  • There is a critical need for evidence-based guidelines for childhood hemorrhagic stroke.
  • Further research is essential to develop effective diagnostic and therapeutic strategies for pediatric hemorrhagic stroke.
  • Understanding the unique aspects of pediatric hemorrhagic stroke is crucial for improving patient outcomes.

Related Concept Videos

Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Stroke: Introduction and Types01:29

Stroke: Introduction and Types

A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Disorders of Hemostasis01:24

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.