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An In Vivo Assessment of Blood-Brain Barrier Disruption in a Rat Model of Ischemic Stroke
12:19

An In Vivo Assessment of Blood-Brain Barrier Disruption in a Rat Model of Ischemic Stroke

Published on: March 11, 2018

[Segmental occlusion of the internal carotid artery with collateral reinjection downstream from the carotid sinus]

G Böge1, O Prodhomme, M Piciche

  • 1Service de chirurgie thoracique et vasculaire, CHU Arnaud-de-Villeneuve, 371 avenue du Doyen-Gaston-Giraud, 34295 Montpellier, France. gudrun.boge@tele2.fr

Journal Des Maladies Vasculaires
|February 6, 2007
PubMed

Insights

A 79-year-old man had complete internal carotid artery sinus obstruction, a rare finding. Collateral circulation from the external carotid artery ensured patency, allowing for potential surgical intervention.

Area of Science:

  • Vascular Surgery
  • Neurology
  • Anatomy

Background:

  • Preoperative evaluation for coronary bypass surgery is crucial for identifying unrelated vascular conditions.
  • Atheromatous obstruction of the carotid artery can lead to stroke, necessitating careful assessment.

Observation:

  • A 79-year-old male asymptomatic patient presented with complete atheromatous obstruction of the internal carotid artery sinus.
  • The internal carotid artery remained patent downstream due to collateral supply from the ipsilateral external carotid artery.

Findings:

  • This anatomical variation is attributed to a persistent embryonic artery, a rare developmental anomaly.
  • Complete obstruction of the internal carotid artery sinus was identified incidentally.

Implications:

  • Recognizing this atypical anatomy is vital for surgical planning in carotid artery interventions.
  • The presence of collateral flow may render surgical intervention feasible in cases of complete obstruction, unlike in typical scenarios.

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