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HLA class I antigen and HLA-A, -B, and -C haplotype frequencies in Uruguayans
Ines Alvarez1, Milka Bengochea, Roberto Toledo
1Laboratorio de Inmunogenética e Histocompatibilidad, Instituto Nacional de Trasplante y Donación de Células, Tejidos y Organos (INDT), Hospital de Clinicas Manuel Quintela, Ave. Italia s/n Piso 4, CP 11600, Montevideo, Uruguay.
Abstract:
HLA class I antigens were determined for 959 unrelated Uruguayans. The predominant HLA alleles were A2, Cw4, and B35, and the most frequently observed two-loci haplotypes were A2-B44 and B35-Cw4. The most frequent three-loci HLA haplotype was A2-Cw5-B44. We compared the Uruguayan sample with similar data from other populations.
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