Related Experiment Video
Updated: Jul 17, 2026

06:08
Genetic Engineering of Dictyostelium discoideum Cells Based on Selection and Growth on Bacteria
Published on: January 25, 2019
Design, synthesis and biological evaluation of a macrocyclic discodermolide/dictyostatin hybrid
Ian Paterson1, Nicola M Gardner
1University Chemical Laboratory, Lensfield Road, Cambridge, UK CB2 1EW. ip100@cam.ac.uk
Abstract:
A 22-membered macrocyclic discodermolide/dictyostatin hybrid has been designed and synthesised; biological evaluation against a range of human cancer cell lines revealed significant levels of growth inhibition.

