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Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH
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Decision of Cirrhosis Using Liver's Ultrasonic Images

Guohui Zhou1, Yuanyuan Wang, Weiqi Wang

  • 1Dept. of Electron. Eng., Fudan Univ., Shanghai.

Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
|February 7, 2007
PubMed

Abstract:

Feature extraction techniques in the ultrasonic images of a liver were studied firstly. As an initial result, total 25 parameters relating to cirrhosis were extracted. They were obtained from the motion curve of the liver in an M-mode image, and from the texture using a B-mode image. Then the efficiency of every parameter was analyzed, and with the use of a feature fusion method a set of 20 useful features was picked out. With these chosen features, a noninvasive automatic decision system for cirrhosis was constructed based on a Fisher linear decision criterion. The clinical application for 43 cases showed that this quantitative system was effective in the diagnosis of cirrhosis.

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Cirrhosis I: Introduction01:23

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Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
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Cirrhosis is a progressive chronic liver injury caused by prolonged inflammation, excessive fibrotic remodeling, and impaired regeneration. Over time, repeated hepatic insults disrupt the liver’s architecture and function, leading to reduced blood flow, impaired bile drainage, and diminished metabolic capacity.Pathophysiology of cirrhosisCirrhosis arises from three main responses to chronic liver damage: inflammation, immune activation, and hepatocyte death. These processes lead to structural...

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