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Biomimetic coating of apatite/collagen composite on Poly L-lactic Acid facilitates cell seeding
Yun Chen1, Arthur T Mak, Min Wang
1Jockey Club Rehabilitation Eng. Center, Hong Kong Polytech. Univ.
Abstract:
Collagen and apatite were co-precipitated as a composite coating on poly L-lactic acid (PLLA) in an accelerated biomimetic process. The coating formed on PLLA films after 24 hours incubation was characterized. Saos-2 osteoblast-like cells were used to evaluate the cell seeding on this biomimetic composite coating. It was shown that cell seeding on PLLA films with the composite coating was greatly improved. PLLA coated with submicron collagen fibrils and submicron apatite particulates can facilitate bone tissue engineering.
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