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Fabrication of Micropatterned Hydrogels for Neural Culture Systems using Dynamic Mask Projection Photolithography
Published on: February 11, 2011
Spatial patterning of fibroblast cells with fabricating holographic patterning on the photoresponsive polymer
Jae Kyoo Lee1, Eunje Jang, Sin-Doo Lee
1Interdisciplinary Program of Biomedical Engineering, Seoul National University, Seoul, Korea; Nano-Bioelectronics and Systems Research Center, Seoul National University, Seoul, Korea.
Abstract:
Micro topographic feature was obtained by laser holographic fabrication on the photoresponsive polymer. Surface feature was localized using photomask for developing two dimensional cellular pattering. Fibroblast cells were cultured and proliferated only on the patterned substrate. Obtained cellular pattering suggests that the laser fabricating with photoresponsive polymer would be applied to regenerating new tissue and developing biomedical device of living cells.
