Functional site analysis in proteins of g protein signaling pathways using fuzzy evolutionary trace method

Zhang Fan1, Liu Zhicheng, Li Xia

  • 1Department of Bioinformatics, Capital University of Medical Sciences.

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Ligand Binding and Linkage

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Protein Families

Protein families are groups of homologous proteins; that is, they have similarities in amino acid sequences and three-dimensional structures. Protein families usually occur because of gene duplication, where an additional copy of a gene is inserted into the genome of an organism.   Mutations that change the amino acids but still allow the protein to be properly synthesized, will lead to new protein family members.   If these new proteins contain similar amino acids in key locations, protein...
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G Protein-coupled Receptors

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Interaction domains in cell signaling
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