Related Experiment Video
Updated: Jul 17, 2026

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models
Published on: November 11, 2020
Simulation of pulmonary pathophysiology during spontaneous breathing
Y C Zhao1, S E Rees, S Andreassen
1Center for Model-based Medical Decision Support, Alborg University, Denmark.
Abstract:
This paper presents a functional model of lung mechanics including a non-linear alveolar pressure volume curve and representation of the work of respiratory muscles during breathing. The model is used to simulate the response to forced inspiration and expiration, and these simulations compared to the standard results of lung function tests routinely performed in departments of lung medicine. The model can simulate the characteristics of inspiratory and expiratory flow profiles seen in normal subjects, and in patients with obstructive or restrictive diseases.
Related Concept Videos
Pulmonary Cycle: Exhalation
Application of Integration: Problem Solving
Pulmonary Ventilation: Inhalation
Boyle's law becomes particularly pertinent when examining respiratory...
Atelectasis II: Pathophysiology
Pneumothorax II: Pathophysiology
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation

