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Updated: Jul 17, 2026
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Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs
Published on: July 23, 2016
Experimental research on the biomechanical properties of the rabbit iris
Xiaohua Liu1, Kunya Zhang, Chen Chen
1Biomechanics Research Center, the Capital University of Medical Sciences, Beijing, China. zcliu@cpums.edu.cn
Abstract
Objective:
To qualify the mechanical properties of the iris during its passive deformation under the condition of glaucoma.
Material And Methods:
Experiments simulating the total pupillary block was performed on isolated rabbit irises to determine the passive mechanical behavior of the intact iris.
Results:
The relationship between the area strain(delta) and the pressure of posterior chamber relative to the anterior chamber(P') was obtained: (P1) was obtained P'+b eb1 delta.
