Related Experiment Video
Updated: Jul 17, 2026

Software for Analysis of Heart Rate and Blood Pressure Time-series Data from the Valsalva Maneuver
Published on: June 27, 2025
Analog signal processing for heart rate extraction
Mingqi Chen1, Olga Boric-Lubecke, Victor Lubecke
1Department of Electrical Engineering, University of Hawaii at Manoa, 2540 Dole Street, Hoholulu, USA. mingqi@hawaii.edu.
Insights
This study introduces a novel analog circuit for real-time heart rate variability (HRV) analysis from ECG signals. This innovation enables more accessible and practical HRV monitoring for home healthcare and implantable devices.
Area of Science:
- Biomedical Engineering
- Cardiovascular Physiology
Background:
- Heart rate variability (HRV) is a crucial biomarker for various medical conditions like heart failure, diabetes, and hypertension.
- Existing HRV analysis relies on pre-recorded, high-resolution ECG data, limiting real-time application.
Purpose of the Study:
- To develop an analog signal processing circuit for real-time HRV data extraction.
- To create a more practical and accessible method for continuous HRV monitoring.
Main Methods:
- Demonstrated an analog circuit designed to process ECG signals.
- The circuit extracts beat-to-beat interval variability in real-time.
- Output is a simple voltage signal for easy monitoring or recording.
Main Results:
- The developed system accurately extracts real-time HRV data.
- The circuit produces a simple output voltage.
- The system is accurate and cost-effective.
Conclusions:
- The analog circuit offers a practical solution for real-time HRV monitoring.
- This technology can enhance home-based healthcare and facilitate the development of implantable devices.
- Low-cost, compact HRV monitoring becomes more feasible.
Abstract:
Heart rate variability (HRV) studies have shown that beat-to-beat interval variability is a strong indicator of a number of medical conditions, including heart failure, diabetes, and hypertension. Current HRV systems typically analyze pre-recorded high resolution ECG recordings. We have demonstrated an analog signal processing circuit which extracts real-time HRV data from EGC signals producing a simple output voltage that is more easily monitored or recorded. The system is accurate and can be produced as a compact low-cost device that can make HRV monitoring more practical for home based health care and implantable devices.
Related Concept Videos
Pulse rhythm
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Factors Influencing Heart Rate
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Electrocardiogram
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and the T...
Correlation between ECG and Cardiac Cycle
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
Special considerations while measuring pulse
Pulse
The pulse serves as a clinical indicator...
