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Updated: Jul 17, 2026

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
Modelling cardiac dynamics with integral pulse frequency modulated units
1School of Mathematics, University of New South Wales, Sydney NSW 2052 Australia.
Abstract:
We investigate a new model for the cardiac system. It embodies the main features of cardiac activity with great flexibility. It can be tuned to suit different cell types, and scaled up or down to represent either a single cell, an aggregate, or whole tissue. We demonstrate its use in the generation of a clinically realistic electrocardiogram (ECG) and other dynamical behaviours such as spiral waves. Our model is computationally economic - about 1000 times faster than ion conductance based models and is thus ideal for doing large scale simulations.
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