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Updated: Jul 17, 2026
Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
Published on: April 14, 2014
Statistical analysis of visual evoked potentials in optic neuritis and ischemic optic neuropathy subjects
G Mukartihal1, S Radhakrishnan, M Ramasubba Reddy
1Biomedical Engineering Division, Department of Applied Mechanics, Indian Institute of Technology Madras, Chennai - 600 036, India.
Abstract:
An effective and clinically relevant parameter for differentiating ischemic optic neuropathy (ION) and optic neuritis (ON) patients using the Visual Evoked Potentials (VEPs) has been identified. In this study, statistical analysis has been carried out on time domain parameters of the VEP waveforms recorded for ION (17 patients) and ON (35 patients) groups. The ratio of the amplitude of P100 component of affected eye to fellow eye showed no significant difference between the two groups. However, the mean P100 absolute latency component of ION patients was found to be significantly (p<0.001) shorter than that of ON patients. This parameter will help the neurologist to clearly classify the diseased patients and help them in early therapy planning.
