Research Progress of Subretinal Implant based on Electronic Stimulation
Wang Xing1, Peng Chenglin, Zhao Zhiqiang
1Key Lab of Biomechanics and Tissue Engineering under the State Education Ministry,Bioenginering College, Chongqing University,400044,China.
Summary
Subretinal prostheses, using microimplants, stimulate the optic nerve to restore vision. This study details the design and fabrication of a microphotodiode array for subretinal implants.
Area of Science:
- Biomedical Engineering
- Neuroscience
- Ophthalmology
Background:
- Retinal prostheses aim to restore vision for individuals with blindness.
- Subretinal implants are a type of retinal prosthesis placed in the subretinal space.
- These devices stimulate the optic nerve to evoke cortical responses.
Purpose of the Study:
- To detail the design and fabrication of a subretinal microimplant.
- To present the microphotodiode array (MPDA) component of the implant.
- To discuss the significance, fundamentals, and future challenges of subretinal prosthesis technology.
Main Methods:
- The study outlines the design concept of the subretinal microimplant.
- Fabrication of the microphotodiode array (MPDA) is described, including its microscopic configuration and electric schematic.
- Detailed fabrication flow using specialized materials and discussion of dimensions are presented.
Main Results:
- The paper details the components of the subretinal implant, including the stimulation chip with MPDA and microelectrodes.
- Fabrication processes and material considerations for the MPDA are elaborated.
- The study provides an overview of the implant's microscopic configuration and electrical properties.
Conclusions:
- Subretinal microimplants represent a significant advancement in retinal prosthesis technology.
- The detailed design and fabrication of the MPDA are crucial for implant functionality.
- Further research and development are needed to address challenges and improve outlook for subretinal prostheses.
