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Published on: June 8, 2022
In vivo Optical Spectroscopy of Acoustically Induced Blood Stasis.
1Departments of Physics and Astronomy, University of Rochester, Rochester, NY 14627. Author Contact: bwiney@pas.rochester.edu.
Summary
Ultrasound can induce blood stasis, a phenomenon previously studied for risks. This research noninvasively demonstrates this effect in mouse tumors and discusses its potential diagnostic applications in optical spectroscopy.
Area of Science:
- Biomedical Engineering
- Medical Imaging
- Optical Spectroscopy
Background:
- Ultrasound-induced blood stasis is a known phenomenon, primarily studied for associated health risks and prevention during medical imaging.
- Previous experimental observations of ultrasound-induced blood stasis have been limited to in vitro or invasive methods.
Purpose of the Study:
- To demonstrate ultrasound-induced blood stasis in vivo using noninvasive optical spectroscopy.
- To explore the potential diagnostic applications of ultrasound-induced blood stasis.
Main Methods:
- Utilized noninvasive optical spectroscopy to observe ultrasound-induced blood stasis.
- Conducted experiments in both tumor and nontumor tissues in murine models.
Main Results:
- Successfully demonstrated ultrasound-induced blood stasis in murine tumor and nontumor tissues.
- Established a noninvasive method for observing this phenomenon.
Conclusions:
- Ultrasound-induced blood stasis can be observed noninvasively using optical spectroscopy.
- This previously undesirable effect of ultrasound holds potential for diagnostic applications.
