Optimization of bulk and surface biosensing in plane stratified configurations

Area of Science:

• Biomedical Engineering
• Optoelectronics
• Biosensing Technology

Background:

• Layered configurations are crucial for biochemical and tissue sensors to measure physical parameters like refractive index.
• Conventional sensitive techniques, such as Surface Plasmon Resonance (SPR), are typically confined to surface sensing within infrared and light wavelengths.

Purpose of the Study:

• To introduce a new broadband absorption biosensing method.
• To demonstrate a highly scalable and sensitive detection approach for both bulk and surface sensing.
• To extend sensing capabilities across a wide range of frequencies, from radio to light.

Main Methods:

• Utilizing Lossy Resonance Modes (LRM) within thin lossy film configurations.
• Developing a broadband absorption-based detection mechanism.
• Implementing a scalable sensor architecture.

Main Results:

• The proposed method enables broadband absorption biosensing.
• The technique is demonstrated to be highly scalable and sensitive.
• Sensing is achievable across diverse frequency bands, including radio and light.

Conclusions:

• Lossy Resonance Modes (LRM) provide a versatile platform for advanced biosensing.
• This new method overcomes the frequency limitations of traditional techniques like SPR.
• The developed biosensor offers broad applicability in various sensing domains.