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Updated: Jul 17, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Experimental study of a complete anastomosis model for the coronary artery bypass
Leok Poh Chua1, Wenfa Ji, Tongming Zhou
1School of Mechanical and Aerospace Engineering, Nanyang Technological University, 639798, Singapore (phone: 0065-6790 5611; fax: 0065-6791 1859;
Abstract:
Local hemodynamics of complete bypass model under steady flow condition was investigated using the instantaneous velocity fields acquired by Particle Image Velocimetry (PIV). At proximal anastomosis a low velocity region was found near the heel along the graft inner wall and a stagnation point was found near the toe. The velocity profile was relatively smooth except slightly skew toward the graft outer wall. Near the occluded end of the distal anastomosis, the fluid was found almost stationary although a weak recirculation occurred. Higher wall shear stress was found to be located at the toe and the artery bed near the toe of the distal anastomosis.

