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Updated: Jul 17, 2026
10:26
Inducing Apical Periodontitis in Mice
Published on: August 6, 2019
Risk factors for developing apical periodontitis in a general population.
L-L Kirkevang1, M Vaeth, P Hörsted-Bindslev
1Department of Oral Radiology, School of Dentistry, University of Aarhus, Denmark. llkirkevang@odont.au.dk
International Endodontic Journal
|February 8, 2007
Summary
High-quality dental restorations are crucial for preventing apical periodontitis (AP). Improving coronal restorations can minimize AP incidence, while root filling quality may influence healing.
Area of Science:
- Endodontics
- Dental Public Health
- Radiology
Background:
- Apical periodontitis (AP) is a common endodontic-inflammatory condition.
- Identifying risk factors for AP is essential for prevention and management.
Purpose of the Study:
- To identify individual and tooth-specific factors linked to the occurrence or persistence of apical periodontitis (AP).
Main Methods:
- A longitudinal study involving radiographic examinations of 616 individuals in 1997 and 2003.
- Analysis of caries, marginal bone level, and tooth restorations for all teeth.
- Logistic regression models to identify predictors of AP at individual and tooth levels.
Main Results:
- Root fillings, coronal restorations, caries, and reduced bone level were associated with AP incidence in individuals.
- Tooth-specific factors included coronal restoration quality/presence and root fillings increasing AP risk.
- Primary caries, reduced bone level, and molar teeth also increased AP risk.
Conclusions:
- High-quality dental restorations are vital to reduce pulpal infection and subsequent AP.
- Focusing on improving coronal restoration quality is key for AP incidence.
- Root filling quality did not impact AP incidence but may affect healing.
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