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Insulin-like growth factors in lysosomal storage disease
S E Jaeggi-Groisman1, W Kiess, H Christomanou
1Department of Medicine, University Hospital, Zürich, Switzerland.
European Journal of Pediatrics
|January 1, 1992
Abstract:
Recent data indicate that insulin-like growth factor II (IGF II) and lysosomal enzymes bind to a common receptor. We measured serum IGF I and II levels in 16 patients with various lysosomal storage disorders. The IGF serum concentrations were normal as long as no marked liver disease was present. Under these conditions no direct interconnection between the lysosomal system and the serum IGF levels was found.