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Updated: Jul 17, 2026
11:20
A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position
Published on: April 1, 2022
Pulmonary homograft endocarditis 19 years after a Ross procedure
H Ashrafian1, M Griselli, M B Rubens
1Department of Cardiothoracic Surgery, Royal Brompton Hospital, London, United Kingdom. ashrafian@email.com
The Thoracic and Cardiovascular Surgeon
|February 8, 2007
Summary
A cat-bite led to Streptococcus agalactiae infection of a pulmonary homograft in a patient 19 years post-Ross procedure. Surgical removal of vegetations and homograft replacement successfully treated the unremitting endocarditis.
Area of Science:
- Cardiology
- Infectious Diseases
- Surgical Innovation
Background:
- The patient had a history of a Ross procedure 19 years prior.
- Acute pulmonary homograft endocarditis is a rare but serious complication.
Observation:
- The patient presented with an infection caused by Streptococcus agalactiae, originating from a cat-bite.
- Large vegetations were observed in the pulmonary trunk and right pulmonary artery, indicating severe infection.
Findings:
- Successful surgical intervention involving pulmonary vegetectomy and homograft replacement was performed.
- The patient's unremitting infection was resolved through this procedure.
Implications:
- This case highlights the risk of endocarditis following homograft procedures, even years later.
- It underscores the importance of considering zoonotic infections in specific clinical contexts.
- The successful surgical management demonstrates a viable treatment option for complex homograft endocarditis.
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