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Related Experiment Video

Updated: Jul 17, 2026

Mass Isolation and In Vitro Cultivation of Intramolluscan Stages of the Human Blood Fluke Schistosoma Mansoni

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[Neuroschistosomiasis: a challenging diagnosis].

P Tarabini-Castellani¹, G González-Chinchón, M Aldamiz-Echebarría

¹Servicio de Medicina Interna, Hospital Txagorritxu, 01009 Vitoria, España. papaoba@yahoo.es

Revista De Neurologia

|February 8, 2007

Summary

Neuroschistosomiasis, a rare parasitic infection, can cause serious neurological issues like myelopathy. Early suspicion and diagnosis are crucial for effective treatment, especially in endemic regions or among travelers.

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Area of Science:

Neurology
Infectious Diseases
Parasitology

Background:

Neuroschistosomiasis is an underdiagnosed neurological disease due to low clinical suspicion.
Common manifestations include seizures, transverse myelitis, myeloradiculopathy, cauda equina syndrome, and Brown-Sequard syndrome.

Observation:

A 27-year-old male from an endemic area presented with atypical neurological symptoms: myelopathy and multifocal neuritis.
Diagnosis was confirmed by epidemiological data, positive serological studies for Schistosoma haematobium, and exclusion of other parasitic infections.
Magnetic resonance imaging revealed hyper signal areas in T2, consistent with neuroschistosomiasis.

Findings:

Schistosoma haematobium was detected in the bladder.
Eosinophils in the sural nerve biopsy indicated a parasitic etiology.
The patient showed clinical and radiological improvement after treatment.

Implications:

Clinicians should suspect neuroschistosomiasis in patients with myelopathy or unexplained neurological symptoms.
Increased global travel and migration necessitate considering parasitic infections like neuroschistosomiasis.
Prompt diagnosis and treatment are vital for managing this uncommon but serious condition.