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Development of a cy3-labeled glucose bioprobe and its application in bioimaging and screening for anticancer agents

Jongmin Park1, Hyang Yeon Lee, Myung-Haing Cho

  • 1Department of Chemistry, College of Natural Science, Seoul National University, Seoul 151-747, Korea.

Angewandte Chemie (International Ed. in English)
|February 8, 2007
PubMed
Abstract

No abstract available in PubMed .

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...