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Perivascular epithelioid cell tumor of the uterus: a case report

S Rammeh Rommani1, A Trabelsi, L Attia

  • 1Department of Pathology, Charles Nicolle Hospital, Tunis, Tunisia. rammehs@yahoo.fr

Pathologica
|February 9, 2007
PubMed

A case of a perivascular epithelioid cell tumor (PEComa) arising in the uterus of a 35-year-old woman is presented. Imaging studies revealed a 5 cm well circumscribed mass in the uterine fundus. The tumor was composed of clear to faintly eosinophilic, epithelioid and spindled cells. Immunohistochemically, most tumour cells were strongly positive for HMB-45, smooth muscle actin and desmine, but negative for epithelial markers, S-100 Protein and neuroendocrine markers. Reevaluation of the patient for signs of tuberous sclerosis complex after the diagnosis gave negative results. At the most recent follow-up 4 months later there was no evidence of recurrence.

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