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Updated: Jul 17, 2026
Histological Quantification of Chronic Myocardial Infarct in Rats
Published on: December 11, 2016
[Forensic pathological significance of immunohistochemical study with CX43 in rats on early myocardial ischaemia]
Li-fang Jin1, Ming-fang Chen, Qiang Zheng
1Institute of Criminal Science, Hangzhou Public Security Bureau, Hangzhou 310031 China.
Objective:
To explore one of evidence for pathologic diagnosis of early myocardial ischaemia.
Methods:
Rats were ligated of the left coronary artery according to a previously documented technique, and heart tissue was sampled at different ischaemia time. The expression of CX43 in myocardial cell was detected by Immunohistochemistry.
Results:
It is showed that the distribution and amount of CX43 positive staining in each group of the myocardial ischaemia was different from that of the control group.
Conclusion:
The changes of CX43 detected by Immunohistochemical methods may be helpful for the diagnosis of early myocardial ischaemia, but further pathologic investigation and research is necessary.
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