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Updated: Jul 17, 2026

Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment
Published on: December 27, 2024
Diagnosis and management of Wegener's granulomatosis in a dog
William Krug1, Sandra Manfra Marretta, Louis-Philippe de Lorimier
1Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, 61802, USA. wvkrug@ncsu.edu
Abstract:
A four-year-old maele/neutered mixed-breed dog was prsented for severe, multifocal, proliferative gingivitis. Histopathologic examination of incisional biopsies supported a diagnosis of Wegener's granulomatosis, an autoimmune vasculitis previously unreported in the veterinary literature. Diagnostic investigations for infectious, neoplastic, or other inflammatory conditions all provided negative results. Management with a combination of immunosuppressive agents resulted in complete resolution and remission of the presenting lesions and associated clinical signs.
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