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Isolation, structure determination, and anti-cancer activity of apoptolidin D

Paul A Wender1, Kate E Longcore

  • 1Department of Chemistry, Stanford University, Stanford, California 94305-5080, USA. wenderp@stanford.edu

Organic Letters
|February 9, 2007
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Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...