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[Ex-PRESS miniature glaucoma implant inserted under a scleral flap in open-angle glaucoma surgery: a retrospective
Journal Francais D'Ophtalmologie
|February 9, 2007
Summary
The Ex-PRESS device, when implanted under a scleral flap for open-angle glaucoma, demonstrated safety and efficacy in lowering intraocular pressure (IOP). This surgical approach showed comparable results to procedures without a flap, reducing erosion risks.
Area of Science:
- Ophthalmology
- Glaucoma Surgery
- Medical Devices
Background:
- Open-angle glaucoma is a leading cause of irreversible blindness.
- Effective management of intraocular pressure (IOP) is crucial to prevent optic nerve damage.
- The Ex-PRESS Glaucoma Filtration Device offers a minimally invasive option for IOP reduction.
Purpose of the Study:
- To evaluate the safety and efficacy of the Ex-PRESS device implanted under a scleral flap in open-angle glaucoma patients.
- To compare surgical outcomes with and without a scleral flap in glaucoma patients.
Main Methods:
- A retrospective case series of 82 Caucasian patients (99 eyes) with open-angle glaucoma.
- Ex-PRESS devices were inserted under a scleral flap, with combined surgery in 28 eyes.
- Ophthalmic examinations, including IOP measurement, were performed pre- and post-operatively with a mean follow-up of 7.5 months.
Main Results:
- Mean IOP decreased from 22.9 mmHg preoperatively to 14.0 mmHg at 6 months and 14.3 mmHg at 1 year.
- An 86.9% success rate (IOP < 21 mmHg) was achieved; 62.6% achieved complete success (IOP < 21 mmHg without medication).
- No infections or device extrusions occurred; athalamia in 6 eyes resolved spontaneously. No significant differences were noted between procedures with or without a scleral flap.
Conclusions:
- The Ex-PRESS device implanted under a scleral flap is safe and effective for glaucoma surgery.
- Utilizing a scleral flap may reduce the risk of corneal erosion.
- Longer follow-up studies are necessary to confirm these findings.
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