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[Pseudotumor cerebri with all-trans retinoic acid. A case report]
Ramzi Jeddi1, Karima Kacem, Raihane Ben Lakhal
1Service d'Hénmatologie clinique, Hôpital Aziza Othmnana.
La Tunisie Medicale
|February 10, 2007
Abstract:
The diagnosis of pseudotumor cerebri (PC) is based on the triad of: (1) papilledema, (2) elevated intracranial pressure with a normal cerebrospinal constituency and (3) normal central nervous system imaging studies. It is an uncommon complication of all-trans-retinoic acid (ATRA) therapy in children treated for acute promyelocytic leukaemia (APL). Its occurrence is rare among adult patients with APL and treated with ATRA . We report a case of an adult with APL who developed PC during induction therapy with ATRA-PC was managed with repeated lumbar punctures and corticotherapy.
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