Related Experiment Video
Updated: Jul 17, 2026

Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis
Published on: May 8, 2021
Urinary proteomics: a tool to discover biomarkers of kidney diseases
Hassan Dihazi1, Gerhard A Müller
1Georg-August University Göttingen, Department of Nephrology & Rheumatology, Robert-Koch-Strasse 40, D-37075 Göttingen, Germany. dihazi@med.uni-goettingen.de
Abstract:
There is intense interest in applying proteomics to urine analysis in order to promote a better understanding of kidney disease processes, develop new biomarkers for diagnosis and detect early factors that contribute to end-stage renal diseases. This interest creates numerous opportunities as well as challenges. To fulfill this task, proteomics requires, in its different stages of realization, various technological platforms with high sensitivity, high throughput and large automation ability. In this review, we will give an overview of promising proteomic methods that can be used for analyzing urinary proteome and detecting biomarkers for different kidney diseases. Furthermore, we will focus on the current status and future directions in investigating kidney diseases using urinary proteomics.
Related Concept Videos
Proteomics
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Urine Studies I: Urinalysis
Microbiota of the Urogenital Tract
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Nephrotic Syndrome II : Assessment and Medical Management
Imaging Studies II: Ultrasonography
