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Chronic daily headache in the pediatric population
Andrew D Hershey1, Jack Gladstein, Paul Winner
1Andrew D. Hershey, MD, PhD Headache Center, Division of Neurology, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. andrew.hershey@cchmc.org.
Current Treatment Options in Neurology
|February 10, 2007
Summary
Children and adolescents with chronic daily headache (CDH) showed significant headache reduction within 6 months. Amitriptyline and topiramate were most effective, suggesting potential for evidence-based treatment approaches.
Area of Science:
- Pediatric Neurology
- Headache Medicine
Background:
- Limited long-term follow-up data exists for pediatric chronic daily headache (CDH).
- Previous short-term studies indicate potential for significant headache frequency reduction in adolescents with CDH.
Purpose of the Study:
- To review existing short-term follow-up data for children and adolescents with chronic daily headache (CDH).
- To identify effective preventive agents for CDH in this population.
- To highlight the need for further research and improved classification for evidence-based treatment.
Main Methods:
- Review of an abstracted report on 24 adolescents with CDH.
- Analysis of headache frequency reduction at 6-month follow-up.
- Assessment of various preventive agents used.
Main Results:
- Over 50% of adolescents experienced a ≥75% reduction in headache frequency at 6-month follow-up.
- One-third of participants showed >90% improvement in headache frequency.
- Amitriptyline and topiramate demonstrated the highest success rates among preventive agents.
Conclusions:
- Short-term follow-up suggests significant efficacy of certain treatments for pediatric CDH.
- Improved classification and multicenter studies are needed to guide evidence-based therapeutic, prophylactic, and behavioral interventions.
- Further research is crucial for managing this debilitating condition in young individuals.
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