Related Experiment Video
Updated: Jul 17, 2026

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
Published on: July 10, 2012
[Lung transplantation: bronchogenic carcinoma in the native lung]
Juan Carlos Peñalver Cuesta1, Carlos Jordá Aragón, Juan Escrivá Peiró
1Servicio de Cirugía Torácica, Hospital Universitario La Fe, Valencia, España. jpenalve@ono.com
Abstract:
In lung transplantation, the presence of bronchogenic carcinoma in the native organ is uncommon, but doubtless affects patient survival, independently of the transplantation process itself. We describe 2 cases in which a primary tumor was found in the explanted lung--1 case of adenocarcinoma in a patient with pulmonary emphysema and 1 case of bronchioloalveolar carcinoma in a patient with idiopathic pulmonary fibrosis. Both patients died due to the recurrence of the neoplastic disease. Distant metastasis was the initial manifestation of the recurrence.

