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Plasma cell granuloma of the middle ear and mastoid. Case report

N C Benton1, H W Korol, L T Smyth

  • 1Department of Otolaryngology-Head and Neck Surgery, Kaiser Permanente Medical Center, Redwood City, California.

The Annals of Otology, Rhinology, and Laryngology
|January 11, 1992
PubMed

Insights

A rare case of plasma cell granuloma (PCG) in the middle ear and mastoid is reported. This non-neoplastic condition presented as a soft tissue mass causing vascular compression, confirmed by imaging and biopsy.

Area of Science:

  • Otolaryngology
  • Pathology
  • Radiology

Background:

  • Plasma cell granuloma (PCG) is a rare benign inflammatory condition.
  • PCG typically affects various organs but is uncommon in the temporal bone.

Observation:

  • A 37-year-old male presented with PCG involving the middle ear and mastoid.
  • Magnetic resonance imaging revealed a homogeneously enhancing soft tissue mass causing significant mastoid bone replacement and vascular compression.

Findings:

  • Surgical resection allowed for detailed histopathological examination.
  • Microscopic analysis showed a predominance of plasmacytes, with histochemical studies confirming a polyclonal origin, indicative of non-neoplastic PCG.

Implications:

  • This case represents the first documented instance of PCG in the middle ear and mastoid.
  • Highlights the importance of considering PCG in the differential diagnosis of temporal bone masses.

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