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Updated: Jul 17, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Surveillance of infection in neonatal intensive care units
1Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK. jim.gray@bch.nhs.uk
Insights
Monitoring neonatal intensive care unit (NICU) infections is crucial for patient safety. While challenges exist, local surveillance of late-onset neonatal sepsis can improve healthcare quality.
Area of Science:
- Healthcare Quality
- Infection Control
- Neonatal Care
Background:
- Infection monitoring is vital for safe healthcare, particularly in intensive care.
- Early-onset neonatal sepsis reflects obstetric care quality, while late-onset sepsis indicates Neonatal Intensive Care Unit (NICU) care quality.
Purpose of the Study:
- To highlight the importance of infection surveillance in Neonatal Intensive Care Units (NICUs).
- To discuss challenges in NICU infection surveillance and the need for effective monitoring strategies.
Main Methods:
- Review of infection surveillance principles and challenges in NICU settings.
- Discussion of the role of early- and late-onset neonatal sepsis in quality assessment.
Main Results:
- NICU infection surveillance faces unique challenges, including defining infections and managing coagulase-negative staphylococci.
- Multi-center programs show promise in reducing healthcare-associated infections on NICUs.
Conclusions:
- Effective surveillance of NICU-acquired infections requires further research to identify optimal methods.
- Local infection surveillance provides significant value in monitoring and improving NICU care quality in the absence of a national program.
Abstract:
Monitoring infection rates is increasingly regarded as an important contributor to safe and high quality health care, especially in intensive care settings. Early-onset neonatal sepsis rates are an important indicator of ante- and intra-partum care, especially as medicalisation of obstetric practice increases. However, surveillance of late-onset neonatal sepsis is required to monitor the quality of Neonatal Intensive Care Unit (NICU)-related care. Infection surveillance on NICUs presents a number of unique challenges, including defining infections, the preponderance of coagulase-negative staphylococci as both pathogens and commensals, and allowing for the influence of important risk factors. Ideally an infection surveillance programme should permit benchmarking of infection rates, and multi-centre programmes have been reported to decrease the incidence of healthcare-associated infections on NICUs. However, further research is required to identify the most clinically- and cost-effective means of surveying NICU-acquired infections before a national programme can be implemented. Until then, considerable value can be obtained from local infection surveillance.
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