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Translocation (8;21) in two cases of refractory anemia with excess of blasts in transformation
E Maserati1, M Casali, F Pasquali
1Biologia Generale e Genetica Medica, Università di Pavia, Italy.
Cancer Genetics and Cytogenetics
|January 1, 1992
Abstract:
We report two cases of refractory anemia with excess of blasts in transformation (RAEB-T) with the translocation (8;21), which is frequent in ANLL but not in myelodysplastic syndromes (MDS). A review of such cases leads us to conclude that myeloproliferative disorders characterized by the t(8;21) may be preceded by an MDS phase.