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Isochromosome (6p) in Waldenstrom's macroglobulinemia
A D White1, R E Clark, A Jacobs
1Department of Haematology, University of Wales College of Medicine, Heath Park, Cardiff.
Cancer Genetics and Cytogenetics
|January 1, 1992
Abstract:
Cytogenetic data on two cases of previously treated Waldenstrom's macroglobulinemia (WM) are presented. An i(6p) was identified in 60 and 56% of bone marrow (BM) metaphases from each patient, respectively. In both cases, i(6p) occurred as part of a complex karyotype but was also observed as the sole abnormality in a proportion of metaphases. The literature on the cytogenetics of WM and the relevance of i(6p) is discussed.