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Evaluation of voiding dysfunctions in children with chronic functional constipation
Erhun Kasirga1, Ipek Akil, Ozge Yilmaz
1Department of Pediatrics, Celal Bayar University Faculty of Medicine, Manisa, Turkey.
Insights
Children with chronic functional constipation (CFC) have a higher risk of urinary tract infections (UTI) and urgency. However, other voiding dysfunctions like nocturnal enuresis were not significantly different between groups.
Area of Science:
- Pediatric Urology
- Gastroenterology
Background:
- Dysfunctional bowel emptying's role in urinary tract disorders like urinary tract infection (UTI), vesicoureteral reflux (VUR), and enuresis remains controversial.
- Constipation can precipitate UTI, enuresis, and VUR through uninhibited bladder contractions.
Purpose of the Study:
- To investigate the prevalence of nocturnal enuresis, UTI, and bladder instability symptoms in children with chronic functional constipation (CFC).
Main Methods:
- A case-control study involving 38 children with CFC and 31 controls.
- Data collection included detailed medical and family history, urinalysis, urine culture, stool analysis, and abdominal ultrasonography.
Main Results:
- The CFC group showed a significantly higher frequency of UTI and urgency compared to the control group.
- No significant differences were observed in the frequencies of urge incontinence, nocturnal enuresis, or genitourinary abnormalities between the groups.
Conclusions:
- Chronic functional constipation (CFC) is associated with an increased risk of UTI and urgency in children.
- Other voiding dysfunctions, such as urge incontinence and nocturnal enuresis, do not appear to be significantly affected by CFC.
Abstract:
There are controversial results about the role of dysfunctional bowel emptying in disorders of the urinary tract like urinary tract infection (UTI), vesicoureteral reflux (VUR) and enuresis. Constipation may cause UTI, enuresis and VUR due to the uninhibited bladder contraction. The aim of this study was to investigate the frequency of nocturnal enuresis, UTI and instability symptoms in chronic functional constipation (CFC). This study included 38 children with CFC and 31 children as the control group. Detailed past and present history of UTIs or symptoms pointing to this diagnosis, enuresis, encopresis, urgency and urge incontinence was obtained from both groups as well as the family history of UTI. Urinalysis, urine culture and stool parasite analysis as well as abdominal ultrasonography were performed on both groups. Age range of the children with CFC was 6-192 months (mean +/- standard deviation (SD) 63.5 +/- 51 months); that of the control group was 4-180 months (mean +/- SD 82 +/- 46.2 months). Frequency of UTI and urgency was significantly higher in the CFC group. However, frequencies of urge incontinence, nocturnal enuresis, and genitourinary abnormalities were not different between the two groups. In conclusion, risk of UTI and urgency is increased in CFC, but that of other voiding dysfunctions like urge incontinence do not change significantly. Therefore, we suggest that UTI and urgency should be questioned in children with CFC and vice versa.
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